I only have Vista (Home Premium) on one machine: a HP Athlon 64 laptop with 2GB RAM, and I have tweaked and prodded the OS to deliver the best performance possible. Truth be told, it was running very nicely, fast, and very stable, with no sundry Vista issues.
Anyway, I tracked down the download of SP1 and installed it today, then did my usual Registry cleanup and defrag (which I do after most software changes). Now the laptop is significantly faster!!
Only issue was that the sound driver got "forgotten" in the update, but that was a simple fix in the Device manager.
Kudo's to Microsoft, it's a significant improvement.